In collaboration with D. Swinkels (Dpt. of Clinical Chemistry, Nijmegen) we analyzed mutations in the HFE protein that cause Hereditary Hemocromatosis. A novel mutation was found. Figures and explanations can be found on the website.
Status: Article accepted by Blood, cells, molecules and diseases" (Blood Cells Mol Dis. 2008 May-Jun;40(3):334-8. Epub 2007 Nov 26.) Click: here for the PubMed abstract.
In addition to the HFE project we also made a model of Hepcidin, a small peptide that is important for iron-regulation. The modeled structure, files and figures were added to the HFE-site.
Status:Figures and models are made and used in an article for Haematologica (2008 Jan;93(1):90-7), see: here for the PubMed abstract. One of the figures even made it to the cover.
More study resulted in another article about hepcidin.
Mass spectrometry analysis of hepcidin peptides in experimental mouse models.PLoS One. 2011 Mar 8;6(3) Abstract| Online full-text| PDF